Do yourself a favor and look into the Eberlestock JP9 Blue Widow. I had the BL's 4500. It creaked like a sonabitch, zippers constantly broke, outter side pockets didn't fit nothing, 100oz bladder had to hang off the backpocket vs keeping it closer to my center of gravity along my back and never fit my torso right. I take it I got a lemon but enough was enough with that pack. I was a big fan until the 45 ruined it for me. I can tell you the BL's 2200 is a badass pack and I've packed out huge amounts of meat in it. The 4500 just didn't do it for me. The Eberle does the job of both of those packs, fits me better and I love the fact I can zip off the spike camp duffel and drop 10-15lbs of camp. It also hauled out elk and deer meat flawlessly for me this year. The Eberle can be very fined tuned in how you can make it fit you. I really like that I can keep my spotter and tripod hooked up and tucked away on the outside of the pack. I'd try a few to see what works best for you.
Attached is what I usually pack. Yes I'm that anal to weigh everything...

Items Weight in Ounces Items in this Load Load Weight
Eberlestock JP9 110.00 x 110.00
Eberlestock Spike Camp Duffel 11.00 x 11.00
Eberlestock JP9 Zip In Panel 6.00 Not Packed
Sure Fire E2 Exec 3.30 x 3.30
Petzl Tikka XP 3.20 x 3.20
Manfrotto Tripod 35.00 Not Packed
Vortex Nomad 60 20-60 Spotter 36.00 Not Packed
Vortex Razor 10X42 Bino 35.00 x 35.00
Vortex Bino Trip Adapt 1.80 Not Packed
Nikon 550 Rifle Hunter Range Finder 6.00 x 6.00
Big Agnes Air Core Insul Pad 22.00 x 22.00
Thermarest Z lite Pad 15.00 Not Packed
WM Megalite 30degree Bag 25.00 x 25.00
ODR Advanced Bivy 39.00 x 39.00
Archers Allen Wrench 3.50 Not Packed
GPS 6.10 x 6.10
Katadyn Pro Filter 14.30 Not Packed
Water Pur Tabs 2.00 x 2.00
Brunton Raptor Stove/Cup/Fuel/Spork 19.00 x 19.00
Camel Pack Bladder w/ filter adapt 8.00 Not Packed
Nalgene Bottle Full (empty 6.6oz) 39.40 Not Packed
Outdoor Edge Deboning Knife 3.30 x 3.30
Buck PBS Knife w/ Sharpener 6.00 x 6.00
4 Alaskan Game Bags / 550 cord / tape 12.00 x 12.00
First Aid Kit 6.40 x 6.40
Maps/Notepad/Pencil 5.40 x 5.40
Elk Calls(reeds,Hootchie,Tube) 7.00 x 7.00
Deer Calls(Rattle bag, Grunt, Bleat) 12.50 Not Packed
Integral Designs Sil Tarp 7.00 Not Packed
Fire Starter, Compass, Whistle, Lighter 6.10 x 6.10
Sitka Rain Gear (Jacket 17, Pants 16 oz) 33.00 x 33.00
Food Weight (apx 27oz each day) 3 days 81.00 x 54.00
Water Weight 100oz Tops 120.00 x 120.00
Mathews Legacy all setup! Not Packed
TOTAL 534.80 Ounces
33.43 Pounds
The excel sheet couldn't be attached so I pasted it. When it shows x number by x number. That just means I checked as part of my package. You'll notice not all items are selected.